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Survival of adult neurons lacking cholesterol synthesis in vivo

BACKGROUND: Cholesterol, an essential component of all mammalian plasma membranes, is highly enriched in the brain. Both during development and in the adult, brain cholesterol is derived from local cholesterol synthesis and not taken up from the circulation. However, the contribution of neurons and...

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Detalles Bibliográficos
Autores principales: Fünfschilling, Ursula, Saher, Gesine, Xiao, Le, Möbius, Wiebke, Nave, Klaus-Armin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769390/
https://www.ncbi.nlm.nih.gov/pubmed/17199885
http://dx.doi.org/10.1186/1471-2202-8-1