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Different Quaternary Structures of Human RECQ1 Are Associated with Its Dual Enzymatic Activity

RecQ helicases are essential for the maintenance of chromosome stability. In addition to DNA unwinding, some RecQ enzymes have an intrinsic DNA strand annealing activity. The function of this dual enzymatic activity and the mechanism that regulates it is, however, unknown. Here, we describe two quat...

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Detalles Bibliográficos
Autores principales: Muzzolini, Laura, Beuron, Fabienne, Patwardhan, Ardan, Popuri, Venkateswarlu, Cui, Sheng, Niccolini, Benedetta, Rappas, Mathieu, Freemont, Paul S, Vindigni, Alessandro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769423/
https://www.ncbi.nlm.nih.gov/pubmed/17227144
http://dx.doi.org/10.1371/journal.pbio.0050020