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Different Quaternary Structures of Human RECQ1 Are Associated with Its Dual Enzymatic Activity
RecQ helicases are essential for the maintenance of chromosome stability. In addition to DNA unwinding, some RecQ enzymes have an intrinsic DNA strand annealing activity. The function of this dual enzymatic activity and the mechanism that regulates it is, however, unknown. Here, we describe two quat...
Autores principales: | Muzzolini, Laura, Beuron, Fabienne, Patwardhan, Ardan, Popuri, Venkateswarlu, Cui, Sheng, Niccolini, Benedetta, Rappas, Mathieu, Freemont, Paul S, Vindigni, Alessandro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769423/ https://www.ncbi.nlm.nih.gov/pubmed/17227144 http://dx.doi.org/10.1371/journal.pbio.0050020 |
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