Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk

The strict spatio-temporal control of Rho GTPases is critical for many cellular functions, including cell motility, contractility, and growth. In this regard, the prototypical Rho family GTPases, Rho, Rac, and Cdc42 regulate the activity of each other by a still poorly understood mechanism. Indeed,...

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Detalles Bibliográficos
Autores principales: Rosenfeldt, Hans, Castellone, Maria Domenica, Randazzo, Paul A, Gutkind, J Silvio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769496/
https://www.ncbi.nlm.nih.gov/pubmed/17224083
http://dx.doi.org/10.1186/1750-2187-1-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769496/
https://www.ncbi.nlm.nih.gov/pubmed/17224083
http://dx.doi.org/10.1186/1750-2187-1-8

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