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Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk
The strict spatio-temporal control of Rho GTPases is critical for many cellular functions, including cell motility, contractility, and growth. In this regard, the prototypical Rho family GTPases, Rho, Rac, and Cdc42 regulate the activity of each other by a still poorly understood mechanism. Indeed,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769496/ https://www.ncbi.nlm.nih.gov/pubmed/17224083 http://dx.doi.org/10.1186/1750-2187-1-8 |