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Agonist mediated internalization of M(2 )mAChR is β-arrestin-dependent

BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) undergo agonist-promoted internalization, but evidence suggesting that the mechanism of internalization is β-arrestin dependent has been contradictory and unclear. Previous studies using heterologous over-expression of wild type or dominant-neg...

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Detalles Bibliográficos
Autores principales: Jones, Kymry T, Echeverry, Maria, Mosser, Valerie A, Gates, Alicia, Jackson, Darrell A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769497/
https://www.ncbi.nlm.nih.gov/pubmed/17224084
http://dx.doi.org/10.1186/1750-2187-1-7