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Agonist mediated internalization of M(2 )mAChR is β-arrestin-dependent
BACKGROUND: Muscarinic acetylcholine receptors (mAChRs) undergo agonist-promoted internalization, but evidence suggesting that the mechanism of internalization is β-arrestin dependent has been contradictory and unclear. Previous studies using heterologous over-expression of wild type or dominant-neg...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769497/ https://www.ncbi.nlm.nih.gov/pubmed/17224084 http://dx.doi.org/10.1186/1750-2187-1-7 |