High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer

BACKGROUND: The development of targeted therapies has created a pressing clinical need for the rapid and robust molecular characterisation of cancers. We describe here the application of high-resolution melting analysis (HRM) to screen for KRAS mutations in clinical cancer samples. In non-small cell...

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Detalles Bibliográficos
Autores principales: Krypuy, Michael, Newnham, Genni M, Thomas, David M, Conron, Matthew, Dobrovic, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769510/
https://www.ncbi.nlm.nih.gov/pubmed/17184525
http://dx.doi.org/10.1186/1471-2407-6-295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769510/
https://www.ncbi.nlm.nih.gov/pubmed/17184525
http://dx.doi.org/10.1186/1471-2407-6-295

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