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Protein kinase C inhibition attenuates vascular ET(B )receptor upregulation and decreases brain damage after cerebral ischemia in rat

BACKGROUND: Protein kinase C (PKC) is known to be involved in the pathophysiology of experimental cerebral ischemia. We have previously shown that after transient middle cerebral artery occlusion, there is an upregulation of endothelin receptors in the ipsilateral middle cerebral artery. The present...

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Detalles Bibliográficos
Autores principales: Henriksson, Marie, Stenman, Emelie, Vikman, Petter, Edvinsson, Lars
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770924/
https://www.ncbi.nlm.nih.gov/pubmed/17212812
http://dx.doi.org/10.1186/1471-2202-8-7