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Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells

BACKGROUND: The sensitizing effects of 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide (DCQ) and ionizing radiation (IR) were determined in four colon cancer cells and in FHs74Int normal intestinal cells. METHODS: Cell cycle modulation, TUNEL assay, clonogenic survival and DNA damage were exa...

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Detalles Bibliográficos
Autores principales: Itani, Wafica, Geara, Fady, Haykal, Joelle, Haddadin, Makhluf, Gali-Muhtasib, Hala
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770925/
https://www.ncbi.nlm.nih.gov/pubmed/17201910
http://dx.doi.org/10.1186/1748-717X-2-1