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Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages

In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We est...

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Detalles Bibliográficos
Autores principales: Jalonen, Ulla, Nieminen, Riina, Vuolteenaho, Katriina, Kankaanranta, Hannu, Moilanen, Eeva
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1775030/
https://www.ncbi.nlm.nih.gov/pubmed/17392586
http://dx.doi.org/10.1155/MI/2006/40691