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The effects of 1α,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion
INTRODUCTION: 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)], the biologically active metabolite of vitamin D(3), acts through an intracellular vitamin D receptor (VDR) and has several immunostimulatory effects. Animal studies have shown that production of some matrix metalloproteinases (MMPs) may b...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
1999
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17774/ https://www.ncbi.nlm.nih.gov/pubmed/11056661 |