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Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is associated with an increased production of a range of cytokines including tumour necrosis factor (TNF)-α and interleukin (IL)-1, which display potent proinflammatory actions that are thought to contribute to the pathogenesis of the disease. Although TNF-α s...

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Detalles Bibliográficos
Autores principales: Joosten, Leo AB, Lubberts, Erik, Helsen, Monique MA, Saxne, Tore, Coenen-de Roo, Christina JJ, Heinegård, Dick, van den Berg, Wim B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17779/
https://www.ncbi.nlm.nih.gov/pubmed/11056663