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In Vitro Derived Dendritic Cells trans-Infect CD4 T Cells Primarily with Surface-Bound HIV-1 Virions

In the prevailing model of HIV-1 trans-infection, dendritic cells (DCs) capture and internalize intact virions and transfer these virions to interacting T cells at the virological synapse. Here, we show that HIV-1 virions transmitted in trans from in vitro derived DCs to T cells principally originat...

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Detalles Bibliográficos
Autores principales: Cavrois, Marielle, Neidleman, Jason, Kreisberg, Jason F, Greene, Warner C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779297/
https://www.ncbi.nlm.nih.gov/pubmed/17238285
http://dx.doi.org/10.1371/journal.ppat.0030004