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Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest

BACKGROUND: Many chemotherapeutic agents have been used to treat pancreatic cancer without success. Apigenin, a naturally occurring flavonoid, has been shown to inhibit growth in some cancer cell lines but has not been studied in pancreatic cancer. We hypothesized that apigenin would inhibit pancrea...

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Detalles Bibliográficos
Autores principales: Ujiki, Michael B, Ding, Xian-Zhong, Salabat, M Reza, Bentrem, David J, Golkar, Laleh, Milam, Ben, Talamonti, Mark S, Bell, Richard H, Iwamura, Takeshi, Adrian, Thomas E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779363/
https://www.ncbi.nlm.nih.gov/pubmed/17196098
http://dx.doi.org/10.1186/1476-4598-5-76