Composition-based statistics and translated nucleotide searches: Improving the TBLASTN module of BLAST

BACKGROUND: TBLASTN is a mode of operation for BLAST that aligns protein sequences to a nucleotide database translated in all six frames. We present the first description of the modern implementation of TBLASTN, focusing on new techniques that were used to implement composition-based statistics for...

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Detalles Bibliográficos
Autores principales: Gertz, E Michael, Yu, Yi-Kuo, Agarwala, Richa, Schäffer, Alejandro A, Altschul, Stephen F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779365/
https://www.ncbi.nlm.nih.gov/pubmed/17156431
http://dx.doi.org/10.1186/1741-7007-4-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779365/
https://www.ncbi.nlm.nih.gov/pubmed/17156431
http://dx.doi.org/10.1186/1741-7007-4-41

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