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Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss

Relaxin, a 6-kDa polypeptide hormone, is a potent mediator of matrix turnover and contributes to the loss of collagen and glycosaminoglycans (GAGs) from reproductive tissues, including the fibrocartilaginous pubic symphysis of several species. This effect is often potentiated by β-estradiol. We post...

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Detalles Bibliográficos
Autores principales: Hashem, Gihan, Zhang, Qin, Hayami, Takayuki, Chen, Jean, Wang, Wei, Kapila, Sunil
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779373/
https://www.ncbi.nlm.nih.gov/pubmed/16784544
http://dx.doi.org/10.1186/ar1978