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Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss
Relaxin, a 6-kDa polypeptide hormone, is a potent mediator of matrix turnover and contributes to the loss of collagen and glycosaminoglycans (GAGs) from reproductive tissues, including the fibrocartilaginous pubic symphysis of several species. This effect is often potentiated by β-estradiol. We post...
Autores principales: | Hashem, Gihan, Zhang, Qin, Hayami, Takayuki, Chen, Jean, Wang, Wei, Kapila, Sunil |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779373/ https://www.ncbi.nlm.nih.gov/pubmed/16784544 http://dx.doi.org/10.1186/ar1978 |
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