Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts

Statins, competitive inhibitors of hydroxymethylglutaryl-CoA reductase, have recently been shown to have a therapeutic effect in rheumatoid arthritis (RA). In RA, synovial fibroblasts in the synovial lining, are believed to be particularly important in the pathogenesis of disease because they recrui...

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Detalles Bibliográficos
Autores principales: Connor, Alison M, Berger, Stuart, Narendran, Aru, Keystone, Edward C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779395/
https://www.ncbi.nlm.nih.gov/pubmed/16774691
http://dx.doi.org/10.1186/ar1968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779395/
https://www.ncbi.nlm.nih.gov/pubmed/16774691
http://dx.doi.org/10.1186/ar1968

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