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Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage

Cartilage destruction in osteoarthritis (OA) is thought to be mediated by two main enzyme families; the matrix metalloproteinases (MMPs) are responsible for cartilage collagen breakdown, whereas enzymes from the 'a disintegrin and metalloproteinase domain with thrombospondin motifs' (ADAMT...

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Detalles Bibliográficos
Autores principales: Davidson, Rose K, Waters, Jasmine G, Kevorkian, Lara, Darrah, Clare, Cooper, Adele, Donell, Simon T, Clark, Ian M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779413/
https://www.ncbi.nlm.nih.gov/pubmed/16859525
http://dx.doi.org/10.1186/ar2013