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Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

Joint cartilage is attacked in both autoimmune inflammatory and osteoarthritic processes. Type IX collagen (CIX) is a protein of importance for cartilage integrity and stability. In this study we have backcrossed a transgenic disruption of the col9a1 gene, which leads to an absence of CIX, into two...

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Detalles Bibliográficos
Autores principales: Carlsen, Stefan, Nandakumar, Kutty Selva, Holmdahl, Rikard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779414/
https://www.ncbi.nlm.nih.gov/pubmed/16813664
http://dx.doi.org/10.1186/ar1989