A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis

Despite decades of research, only a very limited number of matrix metalloproteinase (MMP) inhibitors have been successful in clinical trials of arthritis. One of the central problems associated with this failure may be our inability to monitor the local activity of proteases in the joints since the...

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Detalles Bibliográficos
Autores principales: Simard, Nathalie, Boire, Gilles, de Brum-Fernandes, Artur J, St-Pierre, Yves
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779417/
https://www.ncbi.nlm.nih.gov/pubmed/16859524
http://dx.doi.org/10.1186/ar2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779417/
https://www.ncbi.nlm.nih.gov/pubmed/16859524
http://dx.doi.org/10.1186/ar2014

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