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p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

INTRODUCTION: Endocrine therapy is the most important treatment option for women with hormone receptor-positive breast cancer. The potential mechanisms for endocrine resistance involve estrogen receptor (ER)-coregulatory proteins and cross-talk between ER and other growth factor-signaling networks....

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Detalles Bibliográficos
Autores principales: Yamashita, Hiroko, Toyama, Tatsuya, Nishio, Mariko, Ando, Yoshiaki, Hamaguchi, Maho, Zhang, Zhenhuan, Kobayashi, Shunzo, Fujii, Yoshitaka, Iwase, Hirotaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779473/
https://www.ncbi.nlm.nih.gov/pubmed/16869955
http://dx.doi.org/10.1186/bcr1536