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Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing

BACKGROUND: RNA interference (RNAi) was originally identified as a biological process in which short double-stranded RNA (dsRNA) suppress the expression of genes complimentary to the dsRNA. This cellular intrinsic gene silencing mechanism has subsequently been developed as a useful tool for studies...

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Detalles Bibliográficos
Autores principales: Wang, Shunqing, Shi, Zhenqi, Liu, Wei, Jules, Joel, Feng, Xu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780051/
https://www.ncbi.nlm.nih.gov/pubmed/17187675
http://dx.doi.org/10.1186/1472-6750-6-50