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Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing
BACKGROUND: RNA interference (RNAi) was originally identified as a biological process in which short double-stranded RNA (dsRNA) suppress the expression of genes complimentary to the dsRNA. This cellular intrinsic gene silencing mechanism has subsequently been developed as a useful tool for studies...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780051/ https://www.ncbi.nlm.nih.gov/pubmed/17187675 http://dx.doi.org/10.1186/1472-6750-6-50 |