Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction

AIMS: PTEN is a novel tumour suppressor which exhibits tyrosine phosphatase activity as well as homology to the cytoskeletal proteins tensin and auxilin. Mutations of PTEN have been described in several human cancers and associated with their invasiveness and metastatic properties. Although not mali...

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Detalles Bibliográficos
Autores principales: Pap, Thomas, Franz, Juliane K, Hummel, Klaus M, Jeisy, Elvira, Gay, Renate, Gay, Steffen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17804/
https://www.ncbi.nlm.nih.gov/pubmed/11219390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17804/
https://www.ncbi.nlm.nih.gov/pubmed/11219390

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