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A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics

BACKGROUND: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living cells. So far dynamic metabolic models generally have been based on mechanistic rate equations which often contain so man...

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Detalles Bibliográficos
Autores principales: Nikerel, I Emrah, van Winden, Wouter A, van Gulik, Walter M, Heijnen, Joseph J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781081/
https://www.ncbi.nlm.nih.gov/pubmed/17184531
http://dx.doi.org/10.1186/1471-2105-7-540