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A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics
BACKGROUND: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living cells. So far dynamic metabolic models generally have been based on mechanistic rate equations which often contain so man...
Autores principales: | Nikerel, I Emrah, van Winden, Wouter A, van Gulik, Walter M, Heijnen, Joseph J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781081/ https://www.ncbi.nlm.nih.gov/pubmed/17184531 http://dx.doi.org/10.1186/1471-2105-7-540 |
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