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T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis

INTRODUCTION: A discussion is ongoing regarding the possible role of cartilage-directed autoimmunity as a part of the pathogenesis of rheumatoid arthritis (RA). One possibility is that the association of RA with shared epitope-expressing DR molecules reflects a role for major histocompatibility comp...

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Detalles Bibliográficos
Autores principales: Malmström, Vivianne, Bäcklund, Johan, Jansson, Liselotte, Kihlberg, Jan, Holmdahl, Rikard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17814/
https://www.ncbi.nlm.nih.gov/pubmed/11056672