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Comprehensive genetic and epigenetic analysis of sporadic meningioma for macro-mutations on 22q and micro-mutations within the NF2 locus

BACKGROUND: Meningiomas are the most common intracranial neoplasias, representing a clinically and histopathologically heterogeneous group of tumors. The neurofibromatosis type 2 (NF2) tumor suppressor is the only gene known to be frequently involved in early development of meningiomas. The objectiv...

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Detalles Bibliográficos
Autores principales: Hansson, Caisa M, Buckley, Patrick G, Grigelioniene, Giedre, Piotrowski, Arkadiusz, Hellström, Anders R, Mantripragada, Kiran, Jarbo, Caroline, Mathiesen, Tiit, Dumanski, Jan P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781436/
https://www.ncbi.nlm.nih.gov/pubmed/17222329
http://dx.doi.org/10.1186/1471-2164-8-16