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Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an α-smooth muscle actin-Cre transgenic mouse

BACKGROUND: Epithelial to mesenchymal transition (EMT) in alveolar epithelial cells (AECs) has been widely observed in patients suffering interstitial pulmonary fibrosis. In vitro studies have also demonstrated that AECs could convert into myofibroblasts following exposure to TGF-β1. In this study,...

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Detalles Bibliográficos
Autores principales: Wu, Zhuang, Yang, Leilei, Cai, Lin, Zhang, Min, Cheng, Xuan, Yang, Xiao, Xu, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781437/
https://www.ncbi.nlm.nih.gov/pubmed/17207287
http://dx.doi.org/10.1186/1465-9921-8-1