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Dimerization in protein kinase signaling
The closely related mitogen-activated protein kinases ERK1 and ERK2 have now been shown to have opposing roles in Ras-mediated cell proliferation. I propose that dimerization of these highly related protein kinases could underlie these surprising observations and that this could be a common paradigm...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781521/ https://www.ncbi.nlm.nih.gov/pubmed/16879720 http://dx.doi.org/10.1186/jbiol45 |