Prevention of antigen-induced bronchial hyperreactivity and airway inflammation in sensitized guinea-pigs by tacrolimus.

We examined the effect of the immunosuppressive agent, tacrolimus (FK506), on antigen-induced bronchial hyperreactivity to acetylcholine and leukocyte infiltration into the airways of ovalbumin-challenged guinea-pigs. Subcutaneous injection of 0.5 mg/kg of FK506, 1 h before and 5 h after intra-nasal...

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Detalles Bibliográficos
Autores principales: Lapa e Silva, J R, Ruffié, C, Lefort, J, Nahori, M A, Vargaftig, B B, Pretolani, M
Formato: Texto
Lenguaje:English
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781777/
https://www.ncbi.nlm.nih.gov/pubmed/10704085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781777/
https://www.ncbi.nlm.nih.gov/pubmed/10704085

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