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Acidosis activates complement system in vitro.

We investigated the in vitro effect of different forms of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 micromol/ml blood) or lactic acid (5.5 micromol/ml) to heparin blood (N=12) caused significant activation of C3a and...

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Detalles Bibliográficos
Autores principales: Emeis, M, Sonntag, J, Willam, C, Strauss, E, Walka, M M, Obladen, M
Formato: Texto
Lenguaje:English
Publicado: 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781874/
https://www.ncbi.nlm.nih.gov/pubmed/9927235