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Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7

BACKGROUND: The disabling chronic pain syndrome erythromelalgia (also termed erythermalgia) is characterized by attacks of burning pain in the extremities induced by warmth. Pharmacological treatment is often ineffective, but the pain can be alleviated by cooling of the limbs. Inherited erythromelal...

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Detalles Bibliográficos
Autores principales: Han, Chongyang, Lampert, Angelika, Rush, Anthony M, Dib-Hajj, Sulayman D, Wang, Xiaoliang, Yang, Yong, Waxman, Stephen G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781932/
https://www.ncbi.nlm.nih.gov/pubmed/17239250
http://dx.doi.org/10.1186/1744-8069-3-3