Cargando…

Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage

BACKGROUND: Platelet-activating factor (PAF) is implicated in the neuronal damage that accompanies ischemia, prion disease and Alzheimer's disease (AD). Since some epidemiological studies demonstrate that statins, drugs that reduce cholesterol synthesis, have a beneficial effect on mild AD, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Bate, Clive, Rumbold, Louis, Williams, Alun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781934/
https://www.ncbi.nlm.nih.gov/pubmed/17233902
http://dx.doi.org/10.1186/1742-2094-4-5