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Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage
BACKGROUND: Platelet-activating factor (PAF) is implicated in the neuronal damage that accompanies ischemia, prion disease and Alzheimer's disease (AD). Since some epidemiological studies demonstrate that statins, drugs that reduce cholesterol synthesis, have a beneficial effect on mild AD, we...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781934/ https://www.ncbi.nlm.nih.gov/pubmed/17233902 http://dx.doi.org/10.1186/1742-2094-4-5 |