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System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

The mammalian circadian timing system consists of a master pacemaker in neurons of the suprachiasmatic nucleus (SCN) and clocks of a similar molecular makeup in most peripheral body cells. Peripheral oscillators are self-sustained and cell autonomous, but they have to be synchronized by the SCN to e...

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Detalles Bibliográficos
Autores principales: Kornmann, Benoît, Schaad, Olivier, Bujard, Hermann, Takahashi, Joseph S, Schibler, Ueli
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783671/
https://www.ncbi.nlm.nih.gov/pubmed/17298173
http://dx.doi.org/10.1371/journal.pbio.0050034