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Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Compelling evidence suggests that the transcription factor Foxp3 acts as a master switch governing the development and function of CD4(+) regulatory T cells (Tregs). However, whether transcriptional control of Foxp3 expression itself contributes to the development of a stable Treg lineage has thus f...

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Detalles Bibliográficos
Autores principales: Floess, Stefan, Freyer, Jennifer, Siewert, Christiane, Baron, Udo, Olek, Sven, Polansky, Julia, Schlawe, Kerstin, Chang, Hyun-Dong, Bopp, Tobias, Schmitt, Edgar, Klein-Hessling, Stefan, Serfling, Edgar, Hamann, Alf, Huehn, Jochen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783672/
https://www.ncbi.nlm.nih.gov/pubmed/17298177
http://dx.doi.org/10.1371/journal.pbio.0050038