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Stromelysin-3 over-expression enhances tumourigenesis in MCF-7 and MDA-MB-231 breast cancer cell lines: involvement of the IGF-1 signalling pathway

BACKGROUND: Stromelysin-3 (ST-3) is over-expressed in the majority of human carcinomas including breast carcinoma. Due to its known effect in promoting tumour formation, but its impeding effect on metastasis, a dual role of ST-3 in tumour progression, depending on the cellular grade of dedifferentia...

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Detalles Bibliográficos
Autores principales: Kasper, Grit, Reule, Matthias, Tschirschmann, Miriam, Dankert, Niels, Stout-Weider, Karen, Lauster, Roland, Schrock, Evelin, Mennerich, Detlev, Duda, Georg N, Lehmann, Kerstin E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783860/
https://www.ncbi.nlm.nih.gov/pubmed/17233884
http://dx.doi.org/10.1186/1471-2407-7-12