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Pharmacology and Surface Electrostatics of the K Channel Outer Pore Vestibule

In spite of a generally well-conserved outer vestibule and pore structure, there is considerable diversity in the pharmacology of K channels. We have investigated the role of specific outer vestibule charged residues in the pharmacology of K channels using tetraethylammonium (TEA) and a trivalent TE...

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Detalles Bibliográficos
Autores principales: Quinn, Claire C., Begenisich, Ted
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784061/
https://www.ncbi.nlm.nih.gov/pubmed/17206516
http://dx.doi.org/10.1007/s00232-006-0039-9