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Therapeutic effect of all-trans-retinoic acid (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin

BACKGROUND: Mercuric chloride (HgCl(2)) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitial nephritis, all evident at day 13 of the disease. We assessed the effects...

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Detalles Bibliográficos
Autores principales: Escribese, María M, Conde, Elisa, Martín, Ana, Sáenz-Morales, David, Sancho, David, de Lema, Guillermo Pérez, Lucio-Cazaña, Javier, Sánchez-Madrid, Francisco, García-Bermejo, María L, Mampaso, Francisco M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784079/
https://www.ncbi.nlm.nih.gov/pubmed/17250768
http://dx.doi.org/10.1186/1471-2369-8-3