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Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression

BACKGROUND: Sapphyrin analogues and related porphyrin-like species have attracted attention as anticancer agents due to their selective localization in various cancers, including hematologic malignancies, relative to surrounding tissues. Sapphyrins are electron affinic compounds that generate high y...

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Detalles Bibliográficos
Autores principales: Wang, Zhong, Lecane, Philip S, Thiemann, Patricia, Fan, Qing, Cortez, Cecilia, Ma, Xuan, Tonev, Danielle, Miles, Dale, Naumovski, Louie, Miller, Richard A, Magda, Darren, Cho, Dong-Gyu, Sessler, Jonathan L, Pike, Brian L, Yeligar, Samantha M, Karaman, Mazen W, Hacia, Joseph G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784109/
https://www.ncbi.nlm.nih.gov/pubmed/17233922
http://dx.doi.org/10.1186/1476-4598-6-9