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Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
BACKGROUND: Sapphyrin analogues and related porphyrin-like species have attracted attention as anticancer agents due to their selective localization in various cancers, including hematologic malignancies, relative to surrounding tissues. Sapphyrins are electron affinic compounds that generate high y...
Autores principales: | Wang, Zhong, Lecane, Philip S, Thiemann, Patricia, Fan, Qing, Cortez, Cecilia, Ma, Xuan, Tonev, Danielle, Miles, Dale, Naumovski, Louie, Miller, Richard A, Magda, Darren, Cho, Dong-Gyu, Sessler, Jonathan L, Pike, Brian L, Yeligar, Samantha M, Karaman, Mazen W, Hacia, Joseph G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784109/ https://www.ncbi.nlm.nih.gov/pubmed/17233922 http://dx.doi.org/10.1186/1476-4598-6-9 |
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