SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy

Cyclin D1 is an allosteric regulator for cyclin-dependent kinases 4 and 6 (CDK4/6). The cyclin D/CDK4 kinase promotes G1/S transition through the posttranslational modification and the subsequent inactivation of the retinoblastoma (Rb) protein and related family members (p107 and p130). Accumulation...

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Detalles Bibliográficos
Autores principales: Barbash, Olena, Lin, Douglas I, Diehl, J Alan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790704/
https://www.ncbi.nlm.nih.gov/pubmed/17224055
http://dx.doi.org/10.1186/1747-1028-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790704/
https://www.ncbi.nlm.nih.gov/pubmed/17224055
http://dx.doi.org/10.1186/1747-1028-2-2

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