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Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells
BACKGROUND: The microtubule associated protein tau is the principle component of neurofibrillar tangles, which are a characteristic marker in the pathology of Alzheimer's disease; similar lesions are also observed after chronic alcohol abuse. Formaldehyde is a common environmental contaminant a...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790706/ https://www.ncbi.nlm.nih.gov/pubmed/17241479 http://dx.doi.org/10.1186/1471-2202-8-9 |