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Antifungal Chemical Compounds Identified Using a C. elegans Pathogenicity Assay

There is an urgent need for the development of new antifungal agents. A facile in vivo model that evaluates libraries of chemical compounds could solve some of the main obstacles in current antifungal discovery. We show that Candida albicans, as well as other Candida species, are ingested by Caenorh...

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Detalles Bibliográficos
Autores principales: Breger, Julia, Fuchs, Beth Burgwyn, Aperis, George, Moy, Terence I, Ausubel, Frederick M, Mylonakis, Eleftherios
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790726/
https://www.ncbi.nlm.nih.gov/pubmed/17274686
http://dx.doi.org/10.1371/journal.ppat.0030018