The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model

BACKGROUND: Intranasal inoculation of Streptococcus pneumoniae D39 serotype 2 causes fatal pneumonia in mice. The cytotoxic and inflammatory properties of pneumolysin (PLY) have been implicated in the pathogenesis of pneumococcal pneumonia. METHODS: To examine the role of PLY in this experimental mo...

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Detalles Bibliográficos
Autores principales: García-Suárez, María del Mar, Flórez, Noelia, Astudillo, Aurora, Vázquez, Fernando, Villaverde, Roberto, Fabrizio, Kevin, Pirofski, Liise-Anne, Méndez, Francisco J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790890/
https://www.ncbi.nlm.nih.gov/pubmed/17257395
http://dx.doi.org/10.1186/1465-9921-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790890/
https://www.ncbi.nlm.nih.gov/pubmed/17257395
http://dx.doi.org/10.1186/1465-9921-8-3

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