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The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model

BACKGROUND: Intranasal inoculation of Streptococcus pneumoniae D39 serotype 2 causes fatal pneumonia in mice. The cytotoxic and inflammatory properties of pneumolysin (PLY) have been implicated in the pathogenesis of pneumococcal pneumonia. METHODS: To examine the role of PLY in this experimental mo...

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Detalles Bibliográficos
Autores principales:	García-Suárez, María del Mar, Flórez, Noelia, Astudillo, Aurora, Vázquez, Fernando, Villaverde, Roberto, Fabrizio, Kevin, Pirofski, Liise-Anne, Méndez, Francisco J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790890/ https://www.ncbi.nlm.nih.gov/pubmed/17257395 http://dx.doi.org/10.1186/1465-9921-8-3

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