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Scoring functions and enrichment: a case study on Hsp90

BACKGROUND: The need for fast and accurate scoring functions has been driven by the increased use of in silico virtual screening twinned with high-throughput screening as a method to rapidly identify potential candidates in the early stages of drug development. We examine the ability of some the mos...

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Detalles Bibliográficos
Autores principales: Konstantinou-Kirtay, Chrysi, Mitchell, John BO, Lumley, James A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790905/
https://www.ncbi.nlm.nih.gov/pubmed/17257425
http://dx.doi.org/10.1186/1471-2105-8-27