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Bioinorganic Chemistry in Thyroid Gland: Effect of Antithyroid Drugs on Peroxidase-Catalyzed Oxidation and Iodination Reactions
Propylthiouracil (PTU) and methimazole (MMI) are the most commonly used antithyroid drugs. The available data suggest that these drugs may block the thyroid hormone synthesis by inhibiting the thyroid peroxidase (TPO) or diverting oxidized iodides away from thyroglobulin. It is also known that PTU i...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794076/ https://www.ncbi.nlm.nih.gov/pubmed/17497002 http://dx.doi.org/10.1155/BCA/2006/23214 |